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Figure 13. Photomicrograph (a) of guinea pig tissue reaction to aggregates of cholesterol crystals after an observation period of 32 weeks. The rectangular demarcated areas in (a), (b), and (c) are magnified in (b), (c), and (d), respectively. Note the rhomboid clefts left by cholesterol crystals (CC) surrounded by giant cells (GC) and numerous mononuclear cells (arrowheads in d). AT = adipose tissue, CT = connective tissue. Magnifications: (a) 10x, (b) 21x, (c) 82x, and (d) 220x. (From Nair, 1999.)
