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Figure 12. Cholesterol crystals and cystic condition of apical periodontitis as potential causes for endodontic failures. Overview of a histological section (upper inset) of an asymptomatic apical periodontitis that persisted after conventional root canal treatment. Note the vast number of cholesterol clefts (CC) surrounded by giant cells (GC), of which a selected one with several nuclei (arrowheads) is magnified in the lower inset. D = dentin, CT = connective tissue, NT = necrotic tissue. Magnifications: x68. Upper inset, 11s; lower inset, 412s. (From Nair, 1999.)
