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Figure 10. Fungi as a potential cause of endodontic failures. (a) Low-power overview of an axial section of a root-filled (RF) tooth with a persisting apical periodontitis lesion (GR). The rectangular demarcated areas in (a) and (d) are magnified in (d) and (b), respectively. Note the two microbial clusters (arrowheads in b) further magnified in (c). The oval inset in (d) is a transmission electron microscopic view of the organisms. Note the electron-lucent cell wall (CW), nuclei (N), and budding forms (BU). Magnifications: (a) 35x, (b) 130x, (c) 330x, (d) 60x, and oval inset, 3400x. (Adapted from Nair et al., 1990b.)