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Figure 1. Functional domains of STAT proteins. (A) Schematic diagram of a normal STAT molecule and (B) STAT variant harboring a truncation in the C-terminal transactivation domain. N-terminal (NH₂), Coiled Coil interactive domain (Coiled Coil), DNA-binding domain (DNABD), Linker domain (Linker), Src-Homology 2 domain (SH2), transactivation domain (TAD), phosphotyrosine (pY) and phosphoserine (pS) residues, and C-terminal (COOH) are depicted.

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