Click on image to view larger version.
Figure 2. Genome-wide comparison of transcription factor families in eukaryotes. The relative sizes of the transcription factor families, categorized according to their DNA-binding domain, among Homo sapiens, Drosophila melanogaster, Caenorhabditis elegans, and Saccharomyces cerevisiae are indicated. Data are derived from an analysis of eukaryotic proteomes according to the INTERPRO database, which incorporates Pfam, PRINTS, and Prosite. The transcription factor families shown are the largest in their category out of the 1502 protein families listed by Integrated ProteomicsTM Inc. (IPI). Reproduced with permission from Tupler et al.(2001).
