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Figure 2b. Amino acid sequences surrounding the cleavage sites of DMP1 and DSPP. Vertical arrows indicate cleavages sites. In DMP1, all 4 cleavages occur at the NH2-terminus of the Asp residue (Qin et al., 2003a). Among the 3 cleavage sites in DSPP, 2 major ones are at the NH2-terminus of the Asp residue, while the minor one, as indicated by a smaller arrow, is at the His-Ser bond (Qin et al., 2001b). Amino acid residues are numbered (written on the top of corresponding residues), starting from the NH2-terminus of full-length DMP1 or DSPP, excluding signal peptide.
