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Figure 5. p12DOC-1-mediated cell cycle arrest. p12DOC-1 is a CDK2-associating protein, binds to the monomeric non-phosphorylated form, and suppresses the binding to cyclin E and cyclin A. In addition, p12DOC-1 suppresses DNA replication by binding DNA polymerase-alpha/primase.
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| IADR Journals | Advances in Dental Research ® | Journal of Dental Research ® | Critical Reviews (1990-2004) |
