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Figure 2. Mitogen-activated G1 transition to the S phase. Mitogen stimulation leads to cyclin D1 synthesis. Together with its catalytic partners CDK4 and CDK6, cyclin D1 accelerates G1 progression by phosphorylating pRB.
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| IADR Journals | Advances in Dental Research ® | Journal of Dental Research ® | Critical Reviews (1990-2004) |
