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PARACOCCIDIOIDOMYCOSIS OF THE MOUTH: AN EMERGING DEEP MYCOSIS

Department of Oral Pathology, Dental School of Piracicaba-UNICAMP, Av. Limeira 901, CEP 13.414.903-CP 52, Piracicaba, SP, Brazil;

Crispian Scully

Eastman Dental Institute for Oral Health Care Sciences, University College London, UK

View larger version (113K): [in a new window]   Figure 1. Paracoccidioidomycosis involving the tongue in a 55-year-old woman.

View larger version (101K): [in a new window]   Figure 2. Paracoccidioidomycosis on the palatal and buccal gingivae. The "moriforme" aspect with pinpoint hemorrhages is typical of this disease. This patient also had skin lesions.

View larger version (86K): [in a new window]   Figure 3. Fresh preparation of Paracoccidioides brasiliensis in 10% potassium hydroxide, showing the refractile wall and the formation of new fungi.

View larger version (121K): [in a new window]   Figure 4. Microscopic view of P. brasiliensis phagocytosed by a multinucleated giant cell. The fungi are easily seen by H&E staining.

View larger version (96K): [in a new window]   Figure 5. Gomori-Grocott silver impregnation showing the typical pilot-wheel aspect, characteristic of P. brasiliensis.

View larger version (134K): [in a new window]   Figure 6. Electron micrograph of P. brasiliensis inside a multinucleated giant cell.