CROBM CROBM & JDR Merger
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ball, W. D.
Right arrow Articles by Robinovitch, M. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ball, W. D.
Right arrow Articles by Robinovitch, M. R.

Critical Reviews in Oral Biology & Medicine, Vol 4, 517-524, Copyright © 1993 by International & American Associations for Dental Research

ARTICLES

The B1-immunoreactive proteins of the perinatal submandibular gland: similarity to the major parotid gland protein, RPSP

W. D. Ball, A. R. Hand, J. E. Moreira, J. M. Iversen and M. R. Robinovitch
Department of Anatomy, Howard University College of Medicine, Washington, DC 20059.

The B1-immunoreactive proteins of type III cells of the perinatal rat submandibular gland are immunologically cross-reactive with proteins of both the sublingual and parotid glands; in particular, protein SMG-A appears similar to a major parotid protein. We isolated SMG-A and the parotid protein (known as M1 or leucine-rich protein), prepared polyclonal antibodies to them, and compared their biochemical properties and immunological reactivities. They were identical in their molecular weight on SDS-PAGE (23.5 kDa), tenacious binding to Affi-gel Blue, isoelectric point (pH 4.53), and proteolysis to a 14 kDa peptide: Antibodies to SMG-A showed reactivity with protein SMG-C, a product of the neonatal type I cells, as well as with proteins SMG-B1 and SMG-B2, contrasted with the absence of reactivity of anti-M1 IgG with these proteins. Anti-M1 reacted with the "parotid secretory protein" (PSP) of the mouse, and M1 appears to be the homologue, in the rat, of mouse PSP.


This article has been cited by other articles:


Home page
 Physiol. GenomicsHome page
M. A. Fallon, L. R. Latchney, A. R. Hand, A. Johar, P. A. Denny, P. T. Georgel, P. C. Denny, and D. J. Culp
The sld mutation is specific for sublingual salivary mucous cells and disrupts apomucin gene expression
Physiol Genomics, July 7, 2003; 14(2): 95 - 106.
[Abstract] [Full Text] [PDF]

Home page
 Crit. Rev. Oral Biol. Med.Home page
S. Cha, A.B. Peck, and M.G. Humphreys-Beher
PROGRESS IN UNDERSTANDING AUTOIMMUNE EXOCRINOPATHY USING THE NON-OBESE DIABETIC MOUSE: AN UPDATE
Crit. Rev. Oral. Biol. Med., January 1, 2002; 13(1): 5 - 16.
[Abstract] [Full Text] [PDF]

Home page
 Proc. Natl. Acad. Sci. USAHome page
C. P. Robinson, S. Yamachika, C. E. Alford, C. Cooper, E. L. Pichardo, N. Shah, A. B. Peck, and M. G. Humphreys-Beher
Elevated levels of cysteine protease activity in saliva and salivary glands of the nonobese diabetic (NOD) mouse model for Sjogren syndrome
PNAS, May 27, 1997; 94(11): 5767 - 5771.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
IADR Journals Advances in Dental Research ®
Journal of Dental Research ® Critical Reviews (1990-2004)
Copyright © 1993 Institutional Access Guidelines