| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 Indiana University School of Dentistry, Department of Periodontics and Allied Dental Programs, 1121 West Michigan Street, Indianapolis, IN 46202;
*corresponding author, mkowolik{at}iupui.edu
CONTROVERSY
The evidence supporting the role of the oral cavity as a significant reservoir of Helicobacter pylori is inconclusive. If the oral cavity is a reservoir for H. pylori, is this significant for subsequent gastric infection and thus disease risk? The authors contend that the answer lies, at least in part, in the conduct of studies using more appropriate methodology, designed to test the specific hypotheses being presented.
— Olav Alvares, Editor
Helicobacter pylori infection is one of the most common in man. The bacterium primarily resides in the human stomach, where it plays a significant role in gastric disease. If the spread of H. pylori is to be prevented, an understanding of the transmission process is essential. The oral cavity has been proposed as a reservoir for gastric H. pylori, which has been detected by culture and PCR in both dental plaque and saliva. This review will discuss the evidence for the role of the oral cavity in the transmission of gastric H. pylori. Moreover, the difficulties encountered in addressing this topic, possible directions for future research, and the implications for the dental profession are discussed.
Key words. Helicobacter pylori, transmission, oral, mouth, dental plaque
This article has been cited by other articles:
|
|
 |
|
  W. Delport, M. Cunningham, B. Olivier, O. Preisig, and S. W. van der Merwe A Population Genetics Pedigree Perspective on the Transmission of Helicobacter pylori Genetics, December 1, 2006; 174(4): 2107 - 2118. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. V. Solnick, J. Fong, L. M. Hansen, K. Chang, D. R. Canfield, and J. Parsonnet Acquisition of Helicobacter pylori Infection in Rhesus Macaques Is Most Consistent with Oral-Oral Transmission. J. Clin. Microbiol., October 1, 2006; 44(10): 3799 - 3803. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. J. Olivier, R. P. Bond, W. B. van Zyl, M. Delport, T. Slavik, C. Ziady, J. S. Terhaar sive Droste, A. Lastovica, and S. W. van der Merwe Absence of Helicobacter pylori within the Oral Cavities of Members of a Healthy South African Community J. Clin. Microbiol., February 1, 2006; 44(2): 635 - 636. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Walz, S. Odenbreit, J. Mahdavi, T. Boren, and S. Ruhl Identification and characterization of binding properties of Helicobacter pylori by glycoconjugate arrays Glycobiology, July 1, 2005; 15(7): 700 - 708. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Haukioja, R. Ihalin, V. Loimaranta, M. Lenander, and J. Tenovuo Sensitivity of Helicobacter pylori to an innate defence mechanism, the lactoperoxidase system, in buffer and in human whole saliva J. Med. Microbiol., September 1, 2004; 53(9): 855 - 860. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. D. Eslick Non-gonococcal urethritis, Helicobacter pylori infection and fellatio: a new menage a trois? Microbiology, March 1, 2004; 150(3): 520 - 522. [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
| IADR Journals | Advances in Dental Research ® | Journal of Dental Research ® | Critical Reviews (1990-2004) |
