Figure 5. Schematic design of N15 fusion peptides to display integrin-binding sequences. The functional DGEA and RGD sequences from collagen 1 and osteopontin, respectively, were fused to N15 with a proline linker. Subsequent signal pathway studies have shown that only the DGEA fusion peptide activates ERK1/2 phosphorylation, while both peptides direct FAK phosphorylation.