Figure 3. Hematoxylin-and-eosin-stained sagittal sections through demineralized mouse heads at Day 33 of post-natal life. (A) Fully erupted Cbfa1(+/+) molars in the mandible and (B) Cbfa1(+/-) molars appear fully formed but impacted within the alveolus. (C,D) Higher-magnification views reveal a dense layer of connective tissue and bone overlying the 3 molars (*). Magnifications: A = 4x, B= 2x, C = 20 x, and D = 40x. M1, M2, M3: first, second, and third molars.