Figure 4. Changes in Ca concentration ([Ca]_in) in the solution surrounding the seed crystals as a function of time after delivery of the supersaturated solution. Following the Ca transport along the concentration gradient between the exterior and interior compartments ([Ca]_ex > [Ca]_in), a plateau of the [Ca]_in was attained after 12 hrs of equilibration. The plateau levels, [Ca]_s, are markedly lowered by the presence of seed crystals and the addition of fluoride.