Figure 5. Porphyromonas gingivalis LPS induces NF-B and AP-1 expression in human gingival fibroblasts. The cells were stimulated with LPS from Porphyromonas gingivalis (P-LPS) in the presence or absence of anti-TLR4 monoclonal antibody (anti-TLR4 mAb). Gel mobility shift assay was performed with a biotin-labeled probe [NF-B (A) or AP-1 (B)] (Wang et al., 2000a,b).